Two PhD positions (E13 TV-G-U, 65%)
on the topic “Cysteine metabolic rewiring in vascular aging and regeneration”.
The positions are available from 01.07.2021 for a period of 3 years with the possibility of renewal. The positions are advertised within the framework of a project funded by the German Research Foundation (Emmy Noether Programme), which deals with the consequences of cysteine metabolism in vascular ageing and regeneration (see Circulation. 2019;139:101-114 and Circulation. 2021;143:935-948).
The position requires the following:
• Participation in a research project focusing on understanding endothelial cysteine metabolism on a single cell level in vivo and its effects in vascular aging and regeneration.
• The research project will focus on how cysteine carbons are affecting endothelial metabolism, epigenetics and epiproteomics to regulate cell fate decisions.
• Collection of experimental data, analysis and documentation of results and preparation of material for publication.
• A thematic high-level project in an internationally recognized group, which is part of the Vascular Research Center Frankfurt.
• Rooms, housed in a new research building, with modern facilities and analysis possibilities from integrative physiology to mass spectroscopy.
• National and international networking – The Institute is part of the DFG Cluster of Excellence “CardioPulmonary Institute” and the German Center for Cardiovascular Research (DZHK).
• A completed, very good MSc in biology, biochemistry, pharmacology, molecular medicine or a related discipline.
• Training in cell culture, confocal microscopy, protein post translational modifications and/or single cell methodologies.
• Experience with in vivo models would be beneficial.
• Good self organization and team working abilities.
• While German is not necessary, excellent English is required in both written and spoken language.
Applications with the usual documents (in a single PDF file) and the names and contact details of 3 referees should be submitted in electronic form to Prof. Sofia-Iris Bibli (firstname.lastname@example.org).
This advertisement is online since 07.05.2021