Two PhD positions (E13 TV-G-U, 65%)

on the topic “Cysteine metabolic rewiring in vascular aging and regeneration”.

The positions are available from 01.07.2021 for a period of 3 years with the possibility of renewal. The positions are advertised within the framework of a project funded by the German Research Foundation (Emmy Noether Programme), which deals with the consequences of cysteine metabolism in vascular ageing and regeneration (see Circulation. 2019;139:101-114 and Circulation. 2021;143:935-948).

The position requires the following:

• Participation in a research project focusing on understanding endothelial cysteine metabolism on a single cell level in vivo and its effects in vascular aging and regeneration.

• The research project will focus on how cysteine carbons are affecting endothelial metabolism, epigenetics and epiproteomics to regulate cell fate decisions.

• Collection of experimental data, analysis and documentation of results and preparation of material for publication.

We offer:

• A thematic high-level project in an internationally recognized group, which is part of the Vascular Research Center Frankfurt.

• Rooms, housed in a new research building, with modern facilities and analysis possibilities from integrative physiology to mass spectroscopy.

• National and international networking – The Institute is part of the DFG Cluster of Excellence “CardioPulmonary Institute” and the German Center for Cardiovascular Research (DZHK).

Requirements:

• A completed, very good MSc in biology, biochemistry, pharmacology, molecular medicine or a related discipline.

• Training in cell culture, confocal microscopy, protein post translational modifications and/or single cell methodologies.

• Experience with in vivo models would be beneficial.

• Good self organization and team working abilities.

• While German is not necessary, excellent English is required in both written and spoken language.

Applications with the usual documents (in a single PDF file) and the names and contact details of 3 referees should be submitted in electronic form to Prof. Sofia-Iris Bibli (bibli@vrc.uni-frankfurt.de).

This advertisement is online since 07.05.2021